Program
Wednesday September 22nd
Arrival in the afternoon.
Registration opened at 17:30
| 18:35 | Opening of the workshop |
| Organizing committee | |
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18:40 - 18:50 |
Presentation of the "Tumour targeting, Imaging, Radiotherapies network" of the Cancéropôle Grand Ouest |
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Dimitris Visvikis, LaTIM, National Institute of Health & Clinical Sciences, Brest, France. |
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18:50 - 19:05
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Sponsors communications
Katarzyna Desrocques, MOLECUBES, Ghent, Belgium.
Stéphane Supiot, La Fondation ARC pour la Recherche sur le Cancer, France. |
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19:05 - 20:00
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"Clinical challenges and opportunities to reverse adaptation of the tumour and its ecosystem to radiotherapies" |
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Invited speaker: Irene Virgolini, Department of Nuclear Medicine, Medical University of Innsbruck, Austria. |
| 20:15 | Dinner |
Thursday September 23rd
Session 1: Tumour adaptation to radiotherapies: biological aspects
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8:30 - 9:00 |
“Getting Warburg to be right to improve radiotherapy efficacy” |
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Invited speaker: Olivier Feron, Cancer Translational Research Lab, Pole of Pharmacology and Therapeutics, Institute of experimental and clinical research, UCLouvain, Belgium. |
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9:00 - 10:20 |
4 selected talks |
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“Dissect the tumor microenvironment to battle cancer radioresistance and immune escape“ Ana Canha-Borges, Institute of Investigation and Innovation in Health, University of Porto, Portugal. |
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“Regulatory functions of cancer associated fibroblasts following radiation” Kristin Lode, Faculty of Health Sciences. UiT – The arctic University of Norway, Tromsø, Norway. |
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“In-vitro microvasculature-on-a-chip to study biological alterations due to radiotherapy” Luca Possenti, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. |
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“Voluntary wheel running does not enhance radiotherapy efficiency in a preclinical model of prostate cancer: the importance of physical activity modalities?” Cindy Richard, M2S, University of Rennes, France. |
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| 10:20 - 10:50 | Poster session & Coffee break |
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10:50 - 11:50 |
3 selected talks |
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“Overcoming hypoxia-induced radioresistance of glioblastoma cells by hadrontherapy” Nolwenn Pasquet, Normandie Univ, UNICAEN, CEA, CNRS, ISTCT / CERVOxy group, GIP Cyceron, Caen, France. |
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“Determination of genes implicated in the resistance to proton beam therapy during the treatment of glioblastoma” Jia-Wei Chen, Namur Research Institute for Life Sciences (NARILIS), University of Namur, Belgium. |
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“Assessment of cellular response to internal radiotherapy delivered by Auger-electrons emissions“ Radu Marian Serban, Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering (IFIN-HH, Magurele-Ilfov, Romania. |
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11:50 - 12:00
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Sponsors communications
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Adam Badar– MILabs, Utrecht, The Netherlands.
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| NEXT IRC Transformed & Arronax cyclotron, Nantes, France. | |
| 12:15 | Lunch |
Session 2 : Tumour adaptation to radiotherapies: contribution of imaging
| 14:00 - 14:30 | “Hypoxia imaging and tumour adaptation to radiotherapies” |
| Invited speaker: Heidi Lyng, Oslo University Hospital, The Norwegian Radium Hospital, Department of Radiation Biology, Oslo, Norway. | |
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14:30 - 15:30 |
3 selected talks |
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“A portable gamma camera for the optimization of the patient dosimetry in radioiodine therapy of thyroid diseases” Théo Bossis, University of Paris-Saclay, CNRS/IN2P3, IJCLab, Orsay, France. |
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“In vitro and in vivo evaluation of a 64Cu-radiolabelled anti-CD 138 antibody for Multiple Myeloma imaging and dosimetry” Cassandra Métivier, CHU Nantes, CNRS, Inserm, CRCINA, University of Nantes, France. |
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“Longitudinal and multiparametric study of radiotherapy toxicities on healthy brain in the rat” Fatima-Azzahra Dwiri, Normandie Univ, UNICAEN, CEA, CNRS, ISTCT/CERVOxy group, GIP Cyceron, Caen, France. |
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| 15:30 - 16:00 | Coffee break |
| 16:00 - 17:00 | 3 selected talks |
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“Characterization of hypoxia in brain metastases from lung cancer: from the pre-clinical approach to the clinic“ Jade Fantin, Normandie Univ, UNICAEN, CEA, CNRS, ISTCT/CERVOxy group, GIP Cyceron, Caen, France. |
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“Apparent diffusion coefficient and high b-value Diffusion-Weighted Magnetic Resonance Imaging as biomarkers for tumor response to re-irradiation with Carbon Ion Radiation
Therapy for pelvic rectal recurrences: an explorative analysis” Giula Fontana, National Center for Oncological Hadrontherapy (Fondazione CNAO), Pavia, Italy. |
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“Quantitative Magnetic Resonance Imaging during prostate radiotherapy treatment: preliminary study using a 0.35T MR-linac system” Louis Marage, Centre Georges-François Leclerc, Dijon, France. |
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“99mTc-Tektrotyd, the first radiopharmaceutical for NETs diagnosis at the Nuclear Medicine Service in Kosovo” Armend Jashari, Alma Mater Europaea Campus College "REZONANCA", Prishtine, Republic of Kosovo. |
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| 17:20 - 17:30 | sponsor communication |
| ILIAD SIRIC, Michel Chérel, Nantes, France. | |
| 19:00 | Dinner |
Friday September 24th
Session 3 : Innovative radiation therapeutic strategies
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8:30 - 9:00
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"Irradiation at ultra high dose rate: from the FLASH effect to clinical translation" | |
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Invited speaker: Marie-Catherine Vozenin, Department of Radiation Oncology, Department of Oncology, Lausanne University Hospital and Lausanne University, Switzerland
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9:00 - 10:20 |
4 selected talks |
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“Adaptation of DNA damage repair using DNA-PKcs inhibitors as selective potentiation of peptide receptor radionuclide therapy“ Thom Reuvers, Department of Radiology & Nuclear Medicine, Department of Molecular Genetics, Erasmus MC, Rotterdam, The Netherlands. |
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“CAIX-targeted radionuclide therapy in immunodeficient and immunocompetent mouse models” Simone Kleinendorst, Department of Medical Imaging: Nuclear Medicine, Radboudumc, Nijmegen, The Netherlands. |
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“Anti-HER2 2Rs15d nanobody labeled with 225Ac as a potential molecule for targeted alpha therapy“ Magdalena Rodak, Institute of Nuclear Chemistry and Technology, Warsaw, Poland. |
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“From Ouzo effect to combined chemo-radio-therapies“ Déborah Iglicki, Institut des Sciences Chimiques de Rennes - UMR6226 CNRS, University of Rennes, France. |
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| 10:20 - 10:50 | Poster session & Coffee break | |
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10:50 - 12:30 |
5 selected talks |
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“Improving systemic radiotherapy with radioenhancing nanoparticles” Marine Le Goas, Faculté de Pharmacie, Université de Montréal, Québec, Canada. |
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“Novel therapeutic combination strategies in non-BRAF mutant melanoma“ Malak Sabbah, Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium. |
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“Investigating the interest of proton therapy to obtund radiation-induced lymphopenia in a context of brain tumour irradiation: a preclinical study“ Julie Coupey, Normandie Univ, UNICAEN, CEA, CNRS, ISTCT/CERVOxy group, GIP CYCERON, Caen, France. |
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“In silico feasibility study of carbon ion radiotherapy with simultaneous integrated boost (CIRT-SIB) for head and neck adenoid cystic carcinoma“ Edoardo Mastella, CNAO, National Center for Oncological Hadrontherapy, Pavia, Italy. |
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“Trastuzumab radioimmunoconjugates – promising strategy for selective anticancer therapy“ Paulina Apostolova, Faculty of medical sciences, Goce Delcev University, Stip, Republic of North Macedonia. |
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| 12:30 | Lunch |
Session 4 : Learning and data driven techniques
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14:00 - 14:30
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“Radiomics for immune response characterization under RT treatment” | |
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Invited speaker: Charlotte Robert, Molecular radiotherapy unit, Inserm, Gustave Roussy, University of Paris –Sud, France.
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14:30 - 15:30 |
3 selected talks of young researchers |
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“A mathematical model of the low-grade gliomas response to chemotherapy and radiotherapy: Therapeutic implications“ Luis E. Ayala-Hernández, Departamento de Ciencias Exactas y Tecnología Centro Universitario de los Lagos, Universidad de Guadalajara, Jalisco, Mexico. |
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“Radiation necrosis vs progression in Brain Metastases treated with stereotactic radiosurgery: How to distinguish them using mechanistic mathematical models” Beatriz Ocaña-Tienda, Mathematical Oncology Laboratory (MOLAB), Instituto de Matemática Aplicada a la Ciencia y la Ingeniería, Universidad de Castilla-La Mancha, Ciudad Real, Spain. |
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“Spatial analysis of preclinical dynamic contrast-enhanced ultrasound (DCE-US) images for assessment of tumour response to radiotherapy” Dana Naser Tahboub, Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom. |
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| 15:30 - 16:00 | Poster session & Coffee break | |
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16:00 - 17:00 |
3 selected talks of young researchers |
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“Development and prospective validation of a spatial dose pattern based model predicting acute pulmonary toxicity in patients treated with volumetric arc-therapy for locally
advanced lung cancer“ Vincent Bourbonne, LaTIM UMR 1101 INSERM & Department of Radiation Oncology, University Hospital, Brest, France. |
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“Synthetic tumor insertion using one-shot generative learning for cross-modal image segmentation” Guillaume Sallé, UMR 1101 Inserm LaTIM, UBO, IMT Atlantique & CHRU, Brest, France. |
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“Patient-specific 4DCT respiratory motion synthesis using generative adversarial networks” Yi-heng Cao, UMR 1101 Inserm LaTIM, UBO, IMT Atlantique & CHRU, Brest, France. |
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| 17:00 | Social event |
Saturday September 25th
Session 5 : Futures challenges
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9:00 -9:30
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"Radiobiology of targeted radionuclide therapy: necessity and current challenges" |
| Julie Nonnekens, Dept. of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands. | |
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9:30 -10:00
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"Data science and machine learning in radiomics: past, present, perspectives" |
| Mathieu Hatt, LaTIM, National Institute of Health & Clinical Sciences, University of Brest, France. | |
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| 10:00-10-15 | Coffee break |
| 10:15-11:00 | Round table on industrial point of view |
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11:00-11:45
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Focus on European policy in Oncology and elaboration of call of projects
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| 11:45-12:00 | Awards |
| 12:00 | Lunch |
| 13:10 | End of the workshop - Departure |
Other informations
Scientific sessions:
- Duration of selected talks is 15 minutes and 5 minutes for questions.
Poster session:
- The format of poster is A0.
- Discussion around the posters will be possible during all coffee breaks. Posters should therefore be hanged for the entire duration of the workshop.
