Program

Wednesday September 24th

 Arrival in the afternoon. 

 Registration opened at 18:00

19:00 Opening of the workshop
  Organizing committee
19:05 - 19:10

 

Presentation of the "Tumour targeting, Imaging, Radiotherapies network" of the Cancéropôle Grand Ouest

 

Dimitris Visvikis, Research Director, LaTIM, National Institute of Health & Clinical Sciences, Brest University, France.

 

19:10 - 19:20 

 

 

Sponsor communication

MiLabs 

 

19:20 - 20:15

Plenary conference:

 

Michel Koole, Associate Professor, Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, University Hospitals Leuven, KU Leuven, Leuven, Belgium. 

 

"Quantitative SPECT imaging of alpha and beta emitters"

 

20:30 Dinner

Thursday September 25th

Session 1: Radiobiological responses of external beam radiotherapy

9:00 - 9:30 

 

Invited speaker: Elke Beyreuther, Researcher, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiation Physics, Dresden, Germany.

  "Electron and proton Flash research at the Dresden Platform for ultra-high dose-rate radiobiology"
   

9:30 - 10:10

Selected talks
  Louis Kunz, Radiation Oncology Department, Division of Oncology, Geneva University Hospital & 2LiRR, Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
“FLASH sparing effect is transcriptionally regulated“
   
  Júlia Oliveira Dias, Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
“Next-gen radiotherapy meets immune modulation: the role of exosomes in head and neck cancer resistance”
   
10:10 - 10:40 Poster session & Coffee break
   

10:40 - 11:10

 

 

 

 

Invited speaker: Audrey Bouchet, Researcher, "Radiations, Défense, Santé, Environnement" team, IDEE Epilepsy Institute, Groupement Hospitalier Est-HCL, Lyon, France.
"High-dose-rate X-ray radiotherapy: what imaging and biology have revealed ?"

   
11:10 - 11:50 Selected talks
  Diogo Estêvão, i3S-Institute for Research & Innovation in Health, University of Porto, Portugal.
“Fueling Resistance: Metabolic Rewiring Shields Rectal Cancer from Radiotherapy-induced cell-death”
   
  Ana Canha-Borges, i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
“Decoding Radiotherapy Resistance: The Crucial Role of Macrophages in Triple Negative Breast Cancer”
   
11:50 - 12:05 Sponsors communications
   MEDISO
   Société Française du Cancer
   

 12:05 - 12:15

 

 

 

Anne Royer Moes, IBA SA, RadioPharmaSolutions, Brussels, Belgium & Jean-François Gestin, CRCI2NA, Nantes. 
“At-211 Targeted Alpha Therapy: From Bench to Bedside An European Industry-Academia Partnership Initiative “
   

12:15 

Lunch 

   

Session 2: Innovative Strategies for Molecular Imaging, Targeted Chemotherapy and Radiotherapies

13:45 - 14:15

 

 

Invited speaker: Anna Lucia Tornesello, Researcher, Innovative Immunological Models Unit, Istituto Nazionale Tumori IRCCS, Napoli, Italy.
"Peptide-based probes for molecular imaging in cancer detection"
   

14:15 - 15:15

Selected talks
  Ludovic Le Saux, Laboratory for Radiopharmaceutical Research, Department of Pharmacy and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
“Preclinical PET Imaging of HSP90 Expression Using [¹¹C]Onalespib”
   
  Mathilde Torre, Imagerie Moléculaire et Stratégies Théranostiques, UMR 1240 : Université Clermont Auvergne, Inserm, Clermont-Ferrand, France.
“Development of news therapeutics agents targeting cancer-associated fibroblast”
   
  Luisa Dassi, Molecular Biology and Viral Oncology Unit, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Italy.
“A synthetic membrane-permeating peptide exhibiting inhibitory effects on the proliferation of HPV16-positive cervical cancer cells”
   
15:15 - 15:35 Coffee break

 

15:35 - 16:15

 

 

 

 

 

Selected talks
Valentin Lecomte, General, Organic and Biomedical Chemistry Unit, NMR and Molecular Imaging Laboratory, University of Mons, Belgium.
“Targeted Magnetic Nanoparticles as a Radiosensitizing Agent for Cancer Therapy“

  Nerea Delgado Mayenco, University Medical Center Groningen, University of Groningen, Nuclear Medicine and Molecular Imaging, Groningen, Netherlands.
“Synergistic Approaches in [123I]CC1 Radionuclide Therapy”
   

16:15 - 16:25

Coffee break
   

Session 3: Innovative tracers for imaging and radiotherapy: synthesis, radiochemistry, targeting strategies

 

15:25 - 17:25

 

 

 

 

 

  

Selected talks
Charlene Harriswangler, Universidade da Coruña, CICA - Centro Interdisciplinar de Química e Bioloxía and Departamento de Química, Facultade de Ciencias, 15071, A Coruña, Galicia, Spain.
“CHX-PYAN: A promising chelator for radiopharmaceuticals based on small metal ions”

  Magda Piątkowska, Institute of Nuclear Chemistry and Technology, Warsaw, Poland.
“103/109Pd cyclam-bis(phosphonate) complexes for the bone cancer metastasis therapy“
   
  Antía Freire-García, Universidade da Coruña, Centro Interdisciplinar de Química e Bioloxía (CICA) and Departamento de Química, Facultade de Ciencias, Galicia, Spain.
“Decadentate acyclic chelators for lanthanum radiopharmaceuticals”
   

17:25 - 17:35

Coffee break
   
 17:35 - 18:35 Selected talks
 

Clara Chaize, Groupement d’Intérêt Public ARRONAX & Nantes Université, Inserm, CNRS, Université d’Angers, CRCI2NA, Nantes, France.
“Direct astatination of pre-modified somatostatin analogs”

 

 

Maëlle Deleuziere, Laboratoire Synthèse et physico-chimie de molécules d'intérêt biologique (SPCMIB), Toulouse, France. 
“Development and in vivo evaluation of bimodal Fe@SiO2 nanoparticles for MRI and SPECT imaging”

 

 

Thomas Vangijzegem, General, Organic and Biomedical Chemistry Unit, NMR and Molecular Imaging Laboratory, University of Mons, Mons, Belgium.
“Light and X-ray responsive micellar carriers for triggered cancer therapy assisted by MRI”

 

20:00 Dinner
   

Friday September 26th

 

Session 4: Innovative approaches and models to tackle poor prognosis cancers

8:30 - 9:00

 

  

 

Invited speaker Ahmed Idbaih, Professor, neuro-oncologist, Sorbonne University, Institut du Cerveau, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Neurology service, Paris, France.
"Glioblastoma: current treatments and outlook" 		 
     

9:00 - 10:20

Selected talks  
 

Ana-Gabrielle Stan, U1030, ImmunoRadAI, Inserm, Université Paris-Saclay & Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France.
“Validation of a Prediction Model for Recurrence Patterns in IDH-Mutant Grade 4 Astrocytoma and Glioblastoma Using Advanced MRI Perfusion Biomarkers.“

 
     
  Noémie Joalland, Université de Nantes, CRCI2NA, INSERM, CNRS, Nantes, France.
“Deciphering mechanisms behind hyper-replicative stress to tackle glioblastoma aggressiveness after radiotherapy” 		 
     
  Sofia Tartaro, Fondazione IRCCS Istituto Nazionale dei Tumori, Data Science Unit, Milan, Italy.
“Micro-physio/pathological system on-chip as a preclinical model to replicate pancreatic tumor microenvironment for radiobiological applications” 		 
     
  Camille Van Laere, Nuclear Medical Applications, Belgian Nuclear Research Centre & Laboratory of Radiopharmaceutical Research, KU Leuven, Leuven, Belgium.
“Preclinical Evaluation of [¹⁶¹Tb]Tb-DPI-4452 for CAIX-Targeted Radionuclide Therapy in Pancreatic Cancer” 		 
     

10:20 - 10:50

Poster session & Coffee break

 

10:50 - 11:20

 

 

 

 

Invited speaker. Yan Rolland, Interventional radiologist, LTSI, Laboratoire Traitement du Signal et de l'Image, Centre Eugène Marquis, Rennes, France.
"Selective internal radiotherapy of hepatocellular carcinoma: Towards preoperative dosimetric simulation using AI" 		 
     
 11:20 - 12:00 Selected talks  
  Clarisse Brossard, Comprehensive Cancer Center Eugène Marquis, Rennes, France.
“Design of peptide-modified nanocarriers based on biocompatible polymers to encapsulate radionuclides for diagnosis and/or therapy of hepatocellular carcinoma“ 		 
     
  Agata Malinowska, Institute of Nuclear Chemistry and Technology, Centre of Radiochemistry and Nuclear Chemistry, Warsaw, Poland.
“225Ac-DOTA-GA-panitumumab for targeted radionuclide therapy of triple negative breast cancer” 		 
     
12:00 - 12:15 Coffee break
 		 
     
12:15 - 13:15 Selected talks  
  Julie Pineau, Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, Nantes & Univ Brest, UMR CNRS 6521 CEMCA, Brest, France.
“Theranostic probes using 64Cu/67Cu-matching pair for targeted immuno-PET imaging and radioimmunotherapy“ 		 
     
  Alexandra Fonseca, ICNAS Pharma, University of Coimbra, Portugal.
“Therapeutic Efficacy of [67Cu]Cu-NODAGA-EXs in Osteosarcoma Lung Metastasis” 		 
     
  Khawla Chmeis, Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Orsay, France.
“Harnessing the theranostic potential of natural proteins for radioligand therapy enhanced with radionanoenhencer: utilizing transferrin to combat lung cancer“ 		 
     
13:15 Lunch  
     
14:30 Social event  
     
20:30 Dinner  

Saturday September 27th

Session 5: AI and Computational Advances in Targeted Radiotherapy and Molecular Imaging

 9:00 - 9:30

 

 

 

 

Invited speaker: Charlotte Robert, Associate Professor, Molecular radiotherapy unit, Inserm, Gustave Roussy, University of Paris –Sud, Paris,  France.
“Preserving immune function during radiotherapy using AI and medical physics tools” 

 
     

9:30 - 10:30

Selected talks

 
  Victor Nuttens, Nuclear medicine department, AZORG Aalst & Nuclear Medicine and Molecular Imaging, KU Leuven, Belgium.
“Fast and reliable Lu-177-PSMA SPECT/CT imaging and segmentation for total tumor volume and total lesion activity estimation“ 		 
     
  William Wei, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK.
“AI-enhanced PET-guided SPECT image reconstruction of 177Lu-DOTATATE/ 68Ga-DOTATATE for image-based dosimetry in molecular radiotherapy” 		 
     
  Luis Fernando Torres, University of Rennes, LTSI & INSERM, U1099, Rennes, France.
“Measurement of the Salivary Reserve in 18F-FDG PET Imaging in Patients with Head and Neck Cancer: A Multivariate Analysis for Xerostomia Prediction Using Machine Learning” 		 
     
10:30 - 10:50 Coffee break  
     
10:50 - 11:50
 		Selected talks  
  Jesús J. Bosque, Departamento de Matemática Aplicada, Escuela Técnica Superior de Ingeniería Agronómica, Alimentaria y de Biosistemas (ETSIAAB), Universidad Politécnica de Madrid & Mathematical Oncology Laboratory (MOLAB), University of Castilla-La Mancha (UCLM), Spain.
“Computational simulation of myeloid cell-targeted immunotherapies as adjuvants to radiotherapy in glioma“ 		 
     
  Mohammed Hussein, Université Paris-Saclay, CNRS/IN2P3, IJCLab, Orsay, France.
“SPECT Imaging of 161Tb and 155Tb and Evaluation of the Impact of  156Tb Contamination” 		 
     
  Ewan Morel—Corlu, Univ Rennes, CLCC Eugène Marquis, Inserm, LTSI – UMR 1099 & Therenva, Rennes, France.
“Validation of a new AI-based, fully automated dosimetry software for the planning of the Selective Internal Radiotherapy“ 		 
     
12:00 Lunch & awards  
     
13:15 End of the workshop - Departure  

Other informations

Scientific sessions:

- Duration of selected talks is 15 minutes and 5 minutes for questions.

 

Poster session:

- The format of poster is A0 (vertical).

- Discussion around the posters will be possible during all coffee breaks. Posters should therefore be hanged for the entire duration of the workshop.